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BIOFORGE · SCIENTIFIC WORKSPACE

Not separate tools.One connected workspace.

BioForge brings sequence data, molecular structures and analysis workflows into one project. Keep your data, methods and results connected as your work progresses.

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PRODUCT

Not more tools.
A more coherent way to work.

BioForge reduces disconnected screens and repeated data transfers. Data, methods and outputs remain visible together throughout the work.

The four elements that carry a study stay together.

Starting pointDataExecutionMethodEvaluationReviewScientific recordResult

Workspaces open according to the permissions and access period assigned to your account.

SCIENTIFIC WORKSPACES

Each discipline retains its depth.
All within the same scientific context.

Sequence, biostatistics and 3D structure tools meet in one workspace. Planned engines extend the same system.

Sequence & Genetics

From sequence inspection to genetic design

Inspect DNA, RNA and protein sequences; explore analysis, alignment and design tools in the same project.

Sequence inspection3
  • Sequence Inspector
  • Composition & Properties
  • Sequence Conversion
Genetic analysis3
  • Translation
  • ORF Detection
  • Pattern Search
Alignment & batch processing3
  • FASTA & Batch Processing
  • Pairwise Alignment
  • Alignment Tools
Project sequence tools19
  • Overview
  • Sequence Editor
  • Features
  • Sequence Map
  • Primer Design
  • Versions
  • Comparison
  • Sequence Statistics
  • Restriction Map
  • ORF Explorer
  • Translation / Protein
  • Codon Optimization
  • Assembly Planner
  • Mutation Designer
  • CRISPR / Guide RNA
  • Annotation Search
  • BLAST & Databases
  • Batch Tools
  • Kotyra Design Intelligence
Statistics & Data

From distribution to scientific interpretation

From descriptive statistics to advanced analysis: explore your data, check assumptions and review results in the same workspace.

Basic statistics3

Summarize data, compare groups and examine relationships between variables.

  • Descriptive Statistics
  • Group Comparison
  • Correlation
Checks & sampling3

Check analysis assumptions and manage multiple testing and resampling.

  • Assumption Checks
  • Multiple Testing Correction
  • Bootstrap & Resampling
Advanced analysis3

Explore dose–response relationships, survival and statistical power.

  • Dose Response
  • Survival Analysis
  • Power Analysis
Structure & Drug Discovery

Inspect structure, explore interactions

Explore structural geometry, backbone analysis, surfaces, binding sites and receptor preparation in one workspace.

Structure inspection5

Read structures and inspect geometry, RMSD and backbone using atom and chain selections.

  • Structure Inspector
  • Structure Selection
  • Structure Geometry
  • Structure RMSD
  • Backbone Analysis
Surfaces & interactions4

Explore surfaces, contacts, interfaces, binding sites and cavities.

  • Surface & Contacts
  • Interface Analysis
  • Binding Sites
  • Cavity Analysis
Preparation1

Use receptor preparation tools for structural work.

  • Receptor Preparation
Chemistry & Molecular Design

From molecular identity to 3D comparison

Inspect molecular properties, explore similarity and work with three-dimensional geometry in one workspace.

Molecule inspection4

Read your molecule and inspect its descriptors, standardized representation and identity.

  • Molecule Inspector
  • Molecular Descriptors
  • Molecule Standardization
  • Molecular Identity
Search & similarity2

Compare fingerprint similarity and search for molecular substructures.

  • Fingerprints & Similarity
  • Substructure Search
3D chemistry3

Explore conformers, optimize geometry and compare three-dimensional structures.

  • 3D Conformers
  • Geometry Optimization
  • 3D Comparison
Metabolic Engineering

See flow at the systems level

Import SBML models, inspect flux balance and variability, and compare gene and reaction perturbations within the same model.

Models & import2

Inspect model structure and import SBML files into your workspace.

  • Model Inspector
  • SBML Import
Flux analysis4

Explore flux balance, variability and alternative optima within the same model.

  • Flux Balance Analysis
  • Flux Variability Analysis
  • Parsimonious FBA
  • Alternative Optima
Perturbation6

Compare the model effects of reaction and gene perturbations.

  • Reaction Knockout
  • Gene Knockout
  • Gene Essentiality
  • Double Knockout & Synthetic Lethality
  • MOMA
  • ROOM
Omics & Differential Expression

From omics data to expression patterns

Explore your data in one workspace with tools spanning quality control, experimental design, differential expression, sample exploration and heatmaps.

Data & design2

Review omics data quality and build your experimental design.

  • Omics Data & Quality Control
  • Experimental Design
Expression analysis3

Explore differential expression and review your analysis with diagnostic and result tools.

  • Differential Expression
  • DE Diagnostics
  • DE Result Tools
Data exploration2

Explore relationships between samples and inspect patterns using clustering and heatmaps.

  • Sample Exploration
  • Clustering & Heatmap
Workflows & Automation

Connect engines into reproducible workflows

Start with your research goal; arrange operation nodes, validate and run your workflow, and inspect each step’s results. The three-step sample sequence workflow illustrates this connection.

Research

Choose a research goal, provide input and review the proposed analysis steps.

Workflow Editor

Configure operation nodes, inputs and connections in one editor.

Workflows

Save, validate and run workflows; inspect the status and results of each step.

INSIDE BIOFORGE

Your research.
Your workspace.

Explore BioForge’s seven workspaces, from sequence and genetics to statistics, molecular design and automation.

Sequence & Genetics

DNA, RNA and protein sequences; sequence editing, annotation and genetic analysis.

BioForge 5.0 Demo RC — Sequence map

SCIENTIFIC TRUST ARCHITECTURE

Trust is not added afterwards.
Designed into the work.

Scientific trust rests on visible records. Data ownership, method history and product status are tracked separately.

LOCAL FIRST

Data never leaves the device

Projects, sequences and molecular files remain in the local workspace by default.

Files enter a protected workspace on the device; no flow to an external service is created.

BIOFORGEWORKFLOW VIEW
Sequence files
Molecular structures
Project data
Local workspaceData + method + output

ACCESS & PLANS

From individual research to institutional R&D.

Start with access that fits your needs. Expand the workspace as your team grows.

INDIVIDUALEARLY ACCESS

Researcher

A personal BioForge workspace that keeps data on your device for independent research.

  • Local project workspace
  • Sequence and biostatistics engines
  • Traceable analysis record
Discuss access
ACADEMICACADEMIC PROGRAM

Laboratory

A shared scientific environment for research groups, university laboratories and student teams.

  • Team workspaces
  • Shared method and project records
  • Education and research support
Discuss access
INSTITUTIONALCUSTOM INSTITUTIONAL

Organization

Controlled deployment, institutional support and scalable access for biotechnology R&D teams.

  • Managed deployment
  • Institution-specific configuration
  • Priority technical support
Discuss access
STUDENT ACCESSReach scientific tools from the first step.

We are preparing an accessible BioForge model for students and educational use.

Contact us for access

KOTYRA BIOTECH

Where scientific rigour meets
thoughtful design.

Kotyra Biotech brings scientific disciplines into a shared workspace. BioForge combines sequence, structure, chemistry, biostatistics, omics analyses, metabolic modelling and workflows with project and reporting tools.

Our local-first approach aims to keep researchers in control of their data and make analysis reviewable.

MISSION

Build tools that do not place the burden of scientific method on the user.

We develop approachable tools that help researchers plan their work without losing scientific detail.

VISION

Build a connected ecosystem from research to laboratory operations.

We aim to build a modular platform for academic and R&D teams, adding validated engines and clearly separating available and planned capabilities.

SIK SORULANLAR

About BioForge
clear answers.

PLATFORMWhich scientific workspaces does BioForge bring together?

BioForge brings sequence and genetics, biostatistics, structure and drug discovery, chemistry and molecular design, metabolic engineering, omics analyses and workflows into one workspace. Analyses connect with project history and reporting tools.

ACCESSWhich capabilities are available today?

BioForge Demo is available to download for Windows 10/11 (x64). Sign in to your Kotyra account to download it. Opening workspaces in the app requires a verified account, a valid access period and workspace permissions granted by Kotyra. Registration does not automatically grant access.

LOCAL DATAIs my scientific data uploaded to the cloud?

BioForge is designed as a local-first desktop workspace. The user retains control of project, sequence, structure and analysis files; no unverified cloud service is presented as available.

TRACEABILITYCan an analysis be reproduced later?

Every result is linked to its input, parameters, method and engine version, allowing its production conditions to be reviewed later.

BIOSTATISTICSWhat does the biostatistics workspace cover?

Distributions, effect sizes, confidence intervals and result summaries are reviewed together. On-screen values are illustrative; actual results depend on the data and method.

3D STRUCTUREWhat can I do in the 3D viewer?

Rotate and zoom molecular structures, select atoms and chains, and measure distances and angles. Structure summaries and selection details appear in the same review area.

FILESWhich file formats are supported?

Use FASTA and GenBank for sequences, PDB and mmCIF for structures, operation-specific CSV tables for statistics and supported SBML models for metabolic modelling. Check each module’s input template and format requirements in the in-app help.

TEAMSWill student, academic and institutional access be available?

Contact Kotyra for student, academic or institutional use. The access period and available workspaces are assigned to your account according to your needs. Creating an account alone does not start a demo period or grant workspace permissions.

CONTACT

Start your next scientific study
on stronger foundations.

Contact our team for early access, academic collaborations and institutional discussions.

Emailinfo@kotyrabiotech.comInstagram@kotyrabiotechInstagram Global@kotyrabiotech_global
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Kotyra Biotech

KOTYRA BIOTECH / SCIENTIFIC SOFTWARE

Scientific work,
kept in one context.

ABOUT

Kotyra Biotech develops BioForge, connecting sequence, structure, chemistry, biostatistics, omics analyses and metabolic modelling through workflows.

We keep data control with the user and make the relationship between methods, parameters and outputs visible.

EXPLOREBioForgeHow it worksAccess modelsMission & vision
RESOURCESDocumentationSupportFrequently asked questionsPrivacy
CONTACTinfo@kotyrabiotech.comInstagramInstagram GlobalTürkiye / Independent R&D
LOCAL-FIRSTThe user retains data controlTRACEABLEInputs, methods and outputs togetherMODULARScientific engines share the same project memory
© 2026 Kotyra BiotechThe BioForge Windows demo is available to download.Workspace access depends on account permissions.